Biology / Bio 0781 · Atom · ~20 seconds
G-Protein-Linked Receptors
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A G-protein-linked receptor crosses the membrane seven times and, once bound by ligand, activates a separate G-protein that relays the signal to an ion channel or enzyme.
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Every such receptor shares this seven-pass structure, though its ligand-binding site and G-protein partner differ by cell type.
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The receptor itself does not carry out the response — it only switches the G-protein on.