Biology / Bio 1215 · Atom · ~20 seconds
Origins of Replication
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An origin of replication is a specific DNA sequence where the replication machinery assembles and unwinding begins, opening a replication bubble.
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E. coli's single circular chromosome carries one AT-rich origin of replication, roughly 245 base pairs long.
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An origin marks where replication starts, not where it ends — the replication forks it opens travel outward in both directions.