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Biology  /  Bio 0901  ·  Atom · ~20 seconds

Cancer as a Multi-Hit, Multi-Generational Process

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Cancer typically develops as successive divisions accumulate mutations in proto-oncogenes and tumor suppressor genes, each generation carrying more damage than the last.

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A cell with one damaged tumor suppressor gene may divide normally at first, but its daughters more readily acquire checkpoint-disabling mutations.

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This unit teaches cancer as mechanism, not guidance — naming a failure pathway is not screening or diagnosis.