Biology / Bio 0811 · Atom · ~20 seconds
Signal Transduction Can Alter Metabolism: the Epinephrine Case
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A signaling pathway can alter a cell's metabolism directly, without touching gene expression, by phosphorylating existing metabolic enzymes.
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Epinephrine raises cyclic AMP in muscle cells, and the resulting phosphorylation both activates glycogen breakdown and blocks glycogen synthesis at once.
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Epinephrine is also called adrenaline. The pathway alters existing enzyme activity, not the genes encoding them, so the effect is immediate.