Biology / Bio 0809 · Atom · ~20 seconds
Signal Transduction Can Regulate Gene Expression
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A signaling pathway can regulate gene expression when its final activated protein enters the nucleus and controls transcription or translation there.
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A phosphorylated inhibitor protein can release a bound transcription factor, letting that factor enter the nucleus and switch on RNA transcription.
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Only the pathway's final, nucleus-bound step directly changes gene expression — the earlier cascade steps only relay the signal there.