Chemistry / Chem 2475 · Atom · ~20 seconds
Amides Distinguished from Amines by the Carbonyl
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An amide's nitrogen bonds directly to a carbonyl carbon, unlike an amine's nitrogen, which bonds only to carbon or hydrogen.
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The peptide bond linking amino acids is an amide, formed between one acid's carboxyl and the next's amine group.
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Amides are weaker bases than amines since the carbonyl draws density from nitrogen's lone pair — treating amide nitrogen as basic ignores this.
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