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Biology  /  Bio 0881  ·  Atom · ~20 seconds

The G2 Checkpoint

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The G2 checkpoint bars entry into the mitotic phase unless chromosome replication is complete and the DNA is undamaged.

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A cell whose G2 checkpoint detects incomplete replication halts there and attempts to finish or repair the damage.

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The G2 checkpoint's central concern is DNA integrity — size and reserves are checked too, but damage detection mainly gates this.