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Biology  /  Bio 1597  ·  Atom · ~20 seconds

"The Genome Fully Predicts the Proteome"

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A genome does not fully predict its proteome, because alternative splicing and post-translational modification add diversity the DNA sequence alone does not fix.

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Alternative splicing of one gene's pre-mRNA, per Bio 1331, produces more than one protein from a single sequence.

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A genome sets which proteins are possible; splicing and modification, not the genome alone, determine which proteins a cell actually makes.